Sep 28, 2018 an in vitro organogenesis protocol for carissa carandas l. The aim of this study was to determine the antioxidant and dna damage inhibition potential of a methanolic extract of carissa carandas leaves. Quantification of bioactive compounds and evaluation of. Carissa spinarum has also been used in the ayurvedic medical system because of its therapeutic effects against liver disease, epileptic disease, microbial disease, cytotoxic, viral. The study was performed in order to identify and quantify, by high performance liquid chromatography, bioactive compounds such as vitamin c, carotenoids, anthocyanins, flavonoids and phenolic acids in the fruits of this species.
The extent of tissue damage is the result of the balance between the free radicals generated and the antioxidant protective defense system. A potential medicinal plant mohammad fahim kadir, sadia mahmud, mohammad shahriar on. This protocol produced the maximum number of shoots from aseptic seedlingderived shoot apex explants of c. Apocynaceae is an important fruit commonly known as karonda christs thorn which grows wild in bushes. Kaunda graduate school of the chinese academy of sciences, beijing 39, peoples. Terminalia catappa, carissa carandas, ziziphus nummularia. Antioxidant potential of the polyphenolics in grewia asiatica. Aqueous solutions of the extract and dried extracts from carissa carandas. The anticancer effects was assessed by measuring the renal toxicity markers, antioxidant parameter, proinflammatory markers and histopathology study of the wistar rats.
In this study, the extraction of anthocyanin colorant from karanda fruit carissa carandas l. Kinetics and stoichiometry of reactions between the 2,2diphenyl1picrylhydrazyl dpph stable radical and 25 antioxidant compounds with different structure, molecular weight, number of. Selected conditions for yield maximization consisted of ripen fruits with blackpurple color, material size of thin slices 1. Mutagenicity, cytotoxic and antioxidant activities of. Cytotoxicity was evaluated by hemolytic and brine shrimp assays, whereas ames test ta98 and ta100 was used for. Holarrhena antidysenterica, rauvolfia serpentina, carissa carandas, and tabernaemontana divaricata are the extensively studied plants in this family. Antimicrobial and antioxidant activities of endophytic fungi.
Once the inflammation starts declining from maximum, prostaglandins started to act which results in the. The fruits are astringent due to high pectin content and therefore popular only as preserves. Pdf in vitro antioxidant and dna damage inhibition. Ocimum sanctum, ipomea carnea, delbergia sissoo, lantana camara, carissa carandas and ricinus communis. Quercetin and silver nitrate modulate organogenesis in.
In vietnam, the carissa carandas fruit, often grown in ben tre province, is suggested to be a suitable alternative for lemon due to the sour flavor. The present study was conducted to evaluate the antioxidant and immunostimulant effects of the carica papaya fruit aqueous extract cpf, caricaceae against acrylamide induced oxidative stress and improvement of immune functions which affected by free radicals liberating acrylamide in rats. Ethnopharmacology, phytochemistry, and biotechnological. This report provides scientific evidence to support the health benefit of fruit juice from carissa carandas. Kaunda graduate school of the chinese academy of sciences, beijing. Sesame lignans enhance antioxidant activity of vitamin e in lipid peroxidation systems. While unripe fruits are white, the ripen fruits are dark purple in color. The volatile flavor constituents of karanda fruits carisssa carandas l. Evidencebased complementary and alternative medicine. Oh groups, and redox potential were investigated by recording the loss of dpph absorbance at 515 nm continuously for 10 min. All fractions from fruits, except anthocyanin of c.
The site gives combination of herbs that benefit a disease. It is a straggly, woody, climbing shrub rich in white gummy latex. Phytochemical components of carissa carandas and the. Anticancer, antioxidant, and antibacterial activities of low. To find antioxidant potential of some underutilized fruits, the extracts of their different parts were studied for their total phenolic. It also gives the diseases for which it is best suited. An in vitro organogenesis protocol for carissa carandas l. View enhanced pdf access article on wiley online library html view download pdf for offline viewing. Research article role of dried fruits of carissa carandas as antiinflammatory agents and the analysis of phytochemical constituents by gcms n. In vitro antioxidant, antibacterial, and cytotoxicity activities from karanda. Antioxidant activity and dna damage inhibition in vitro by. The ripe fruit of carissa carandas can be used as a novel source of functional beverage in food manufacture because they possess not only antioxidant properties, but also an anti. Antioxidant, cytotoxic and antineoplastic effects of carissa. Antioxidant, physicochemical, microbiological, and sensory.
Carissa carandas leaves antineoplastic cytotoxic antioxidant for scienti. Antioxidant evaluations of polar and nonpolar fractions of cajanus cajan seeds 10 february 2015 journal of medicinal plants research, vol. Antioxidant activity and nutraceutical property of the. Names of carissa carandas in various languages of the world are also given. Optimization of total anthocyanin content, stability and antioxidant. One hundred and fifty compounds were identified in the aroma concentrate, of which isoamyl alcohol, isobutanol and. The present study demonstrated that the low molecular weight subfractions iii exhibited the strongest inhibitory activity towards breast. Pdf antioxidant activity and nutraceutical property of the fruits of. Lignans and a sesquiterpene glucoside from carissa carandas stem. Physiological changes in karanda carissa carandus l. Aqueous solutions of the extract and dried extracts from carissa carandas fruit were evaluated for stability at two temperature conditions, namely room temperature 30 2 c and 45 c. Pdf phytochemical studies on antioxidant activities of two types of. It list common diseases and suggest herbs that will benefit that disease.
The aims of this research were to evaluate the antimicrobial and antioxidant activities of extracts from endophytic fungi, identify the potential fungal isolates by phylogenetic analysis and analyze the composition of the potential crude extract by gas chromatographymass. Volatile flavor constituents of karanda carissa carandas l. Research article role of dried fruits of carissa carandas. Adaptogenic activity of lanostane triterpenoid isolated from carissa carandas fruit. Antioxidant activity and dna damage inhibition in vitro by a. Antioxidant, cytotoxic and antineoplastic effects of. The karanda plant carissa carandas is an evergreen shrub belonging to the apocynaceae family. The carissa carandas fruit is rich in iron, vitamin c, and possesses high antioxidant activity 5,6. Antioxidant activity and dna damage inhibition in vitro by a methanolic extract of carissa carandas apocynaceae leaves. Is a large dichotomously branched evergreen shrub with short stem and strong thorns in pairs, belonging to the family apocynaceae. Pdf in vitro antioxidant and dna damage inhibition activity. Pdf hidden potential of natural herb carissa carandas karonda. This is the first report of endophytic fungi derived from carissa carandas producing bioactive compounds in thailand.
Antimicrobial and antioxidant activities of endophytic. There is lack of reports in literature on the physicochemical characteristics and antioxidant potential of. Antimicrobial polyphenols from small tropical fruits, tea. Ricinus communis castor plant is a potent medicinal plant, which is commonly used in the treatment of various ailments. Effects of abscisic acid on capsanthin levels in pepper. The dried fruits of carissa carandas could be used as a source of potential antioxidant or functional food material. Volatile flavor constituents of karanda carissa carandas. Presentation mode open print download current view. In this experiment first the researchers induced edema by injecting 1% carrageenan, thereby caused the release of autacoids, histamine, and 5hydroxy tryptamine 5ht. Anticancer, antioxidant, and antibacterial activities of. There is lack of reports in literature on the physicochemical characteristics and antioxidant potential of the karanda fruit. A series of antioxidant concentrations was tested to determine linear response. Uses, benefits, cures, side effects, nutrients in carissa carandas. Changes in phytonutrients and antioxidant properties of.
In this study, antioxidant, chemical, microbiological, and sensory attributes changes taking place during the production of probiotic yoghurt using pulp of soursop annona muricata, sweetsop annona squamosa, and custard apple annona reticulata were evaluated. The effectiveness of dried cranberries vaccinium macrocarpon in men with lower urinary tract symptoms volume 104 issue 8 ales vidlar, jitka vostalova, jitka ulrichova, vladimir student, david stejskal, richard reichenbach, jana vrbkova, filip ruzicka, vilim simanek. The methanol extract of carissa carandas leaves melc was applied on dpph and abts experiments to determine its antioxidant activity. Antioxidant activity and dna damage inhibition in vitro.
Antiinflammatory and antioxidant activities of naringin isolated from. None of the studies have reported the antioxidant activities associated to the various polyphenolic fractions of g. The plant used locally in indian and chinese system of medicines to cure various diseases. Characterization of bioactive compounds in eugenia. The leaves and roots of plant were extracted by cold percolation method using organic solvents such as ethanol, methanol and distilled water. This study verifies the antioxidant and antitumor characteristics of brazilein in skin cancer cells and is the first time to elucidate the inhibition mechanism of adipocyte differentiation. Carissa carandas linn is an evergreen diffuse and spiny shrub occurring throughout the country. Reevaluation of the 2,2diphenyl1picrylhydrazyl free. Carissa edulis is a plant used in the management of oxidative stress and inflammatory related disorders such as malaria, rheumatism inflammation, and cardiovascular diseases. Optimization of total anthocyanin content, stability and antioxidant evaluation of the anthocyanin extract from vietnamese carissa. Carissa carandas is a useful food and medicinal plant of india, found to be widely. Mar 25, 2018 holarrhena antidysenterica, rauvolfia serpentina, carissa carandas, and tabernaemontana divaricata are the extensively studied plants in this family. The methanol extract showed significant antioxidant activity compared to petroleum ether due to the presence of phenolic compounds and flavonoid in the.
Hence to validate its traditional use, the present study has envisaged screening different solvents extract of carissa carandas fruit for their. Potential health benefits of carissa carandas dried fruit. Utilization of biotechnological approaches for germplasm. Carissa carandas, antioxidant activity, dna damage. Antibacterial activity directed isolation of compounds from punica granatum. The present study evaluates the total phenolic content, antioxidant capacity dpph. How carissa carandas is effective for various diseases is listed in repertory format. Pdf hidden potential of natural herb carissa carandas. Quantification of bioactive compounds and evaluation of the. The present study was conducted to appraise the cytotoxicity and mutagenicity of r. Carissa edulis is a plant used in the management of oxidative stress and.
Read physiological changes in karanda carissa carandus l. Products in amphawa district abstract this study has the purpose to find antioxidant and antibacterial activity of carissa carandas, to develop karonda glycerin soap, canned karonda juice and to improve products in ampawa district. Antibacterial activity directed isolation of compounds. The fruits are rich in vitamin a, c, potassium, antioxidant polyphenols, dietary fibers and are low in calories, etc. In vitro the cytotoxic effect of melc was evaluated against colonic adenocarcinoma cell lines sw480 and sw48 whereas in vivo its antineoplastic property was tested against ehrlich ascites carcinoma eac. Jan 23, 2015 fruit ripening is the process resulting in changes in color, taste and texture, which make the fruit acceptable for consumption. Activityguided investigation of carissa carandas l. Carissa carandas belongs to family apocynaceae, known as karaunda, used as a prophylactic agent due to its medicinal properties i. Karonda is a widely used medicinal plant by tribals throughout india and popular in various indigenous system of medicine like ayurveda, unani and homoeopathy. For scientific clarification of some traditional uses, this study was designed to explore the antioxidant, cytotoxic and antineoplastic properties of leaf extract of carissa carandas linn. To our knowledge, there is no report on antioxidant studies. A study was conducted to study changes in phytonutrients, viz. The plant is very valuable for the indian system of medicine particularly ayurveda.
List of various diseases cured by carissa carandas. In vitro antioxidant and dna damage inhibition activity of methanolic extract of carissa carandas apocynaceae leaves. Handique, evaluation of in vitro antioxidant potential of carissa carandas genotype found in ne india, international journal of scientific research in science and technology ijsrst, online issn. Paper title development of karonda carissa carandas l. Pdf the present work was designed to study the antioxidant potential of various parts of carrisa carandas using different assay systems. Sep 15, 2015 antioxidants and health the womens antioxidant cardiovascular study found no beneficial effects of vitamin c, vitamin e, or beta carotene supplements on cardiovascular events heart attack, stroke, or death from cardiovascular diseases or the likelihood of developing diabetes or cancer in more than 8,000 female health professionals. Brazilein, a natural, biologically active compound from caesalpinia sappan l. Research on medicinal plants and traditional medicine in. Fruit ripening is the process resulting in changes in color, taste and texture, which make the fruit acceptable for consumption. Evidencebased complementary and alternative medicine hindawi. Antioxidant properties of karanda carissa carandas linn. Quantification of bioactive compounds and evaluation of the antioxidant.
The aim of this study is to investigate in vitro the anticancer, antioxidant, and antibacterial activities of three low molecular weight subfractions i, ii and iii isolated from secondary metabolites produced by the wood degrading fungus cerrena unicolor. Agnps showed peak at 420 nm in uv spectroscopy with spherical structure and gives. Research further suggests that lipoic acid has a sparing effect on other antioxidants. The aim of this study was to determine the antioxidant and dna.
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